Macrocyclic ferrocenyl-bisimidazoline palladacycle dimers as highly active and enantioselective catalysts for the aza-claisen rearrangement of Z-configured N-para-methoxyphenyl trifluoroacetimidates

被引：98

作者：

Jautze, Sascha ^{[1
]}

Seiler, Paul ^{[1
]}

Peters, Rene ^{[1
]}

机构：

[1] ETH, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 08期

关键词：

aza-Claisen rearrangement; cyclopalladation; ferrocenes; imidazoline ligands; Overman rearrangement;

D O I：

10.1002/anie.200603568

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) In just four steps from ferrocene, macrocyclic ferrocenyl bispalladacyles have been synthesized by using a diastereoselective biscyclopalladation reaction as the key step. The complexes not only possess a fascinating structure but are also the first highly active catalysts for the title reaction (see scheme), requiring as little as 0.1 mol% of catalyst for most of the substrates. Ts = toluene-4-sulfonyl. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1260 / 1264

页数：5