The chromatoid body: a germ-cell-specific RNA-processing centre

被引：238

作者：

Kotaja, Noora

Sassone-Corsi, Paolo

机构：

[1] Univ Turku, Inst Biomed, Dept Physiol, Turku 20520, Finland

[2] Univ Calif Irvine, Sch Med, Dept Pharmacol, Irvine, CA 92697 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2007年 / 8卷 / 01期

关键词：

D O I：

10.1038/nrm2081

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The chromatoid body, a unique cloud-like structure of male germ cells, moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades. Recent findings indicate that microRNA and RNA-decay pathways converge to the chromatoid body. This highly specialized structure might function as an intracellular focal domain that organizes and controls RNA processing in male germ cells.

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页码：85 / 90

页数：6

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