A simple and efficient enantioselective synthesis of piperidine alkaloids dihydropinidine and isosolenopsins A, B and C

被引：51

作者：

Ciblat, S

Besse, P

Papastergiou, V

Veschambre, H

Canet, JL

Troin, Y

机构：

[1] Univ Blaise Pascal, Ecole Natl Super Chim Clermont Ferrand, Lab Chim Heterocycles & Glucides, EA 987, F-63174 Aubiere, France

[2] Univ Clermont Ferrand 2, CNRS, UMR 6504, Lab Synthese Electrosynthese & Etud Syst Interet, F-63177 Clermont Ferrand, France

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 10期

关键词：

D O I：

10.1016/S0957-4166(00)00162-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A diastereospecific intramolecular Mannich-type reaction, involving enantiopure amine 4 and achiral aldehydes, is employed as the key step of an efficient total enantioselective synthesis of five piperidine alkaloids. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2221 / 2229

页数：9

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