Haliclonyne, a new highly oxygenated polyacetylene from the marine sponge Haliclona species

被引：24

作者：

Chill, L

Miroz, A

Kashman, Y ^{[1
]}

机构：

[1] Tel Aviv Univ, Sch Chem, IL-69978 Tel Aviv, Israel

[2] Underwater Observ & Aquarium, Elat, Israel

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 04期

关键词：

D O I：

10.1021/np990342m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Haliclonyne (1), a new polyacetylene carboxylic acid, has been isolated from the marine sponge Haliclona sp. collected in the Gulf of Eilat. The structure of haliclonyne, a C-47 oxo-octahydroxy-dienetetrayne carboxylic acid, was elucidated by interpretation of NMR and mass spectra of 1 and two of its derivatives.

引用

收藏

页码：523 / 526

页数：4

相关论文

共 20 条

[1] Oriamide, a new cytotoxic cyclic peptide containing a novel amino acid from the marine sponge Theonella sp. [J].

Chill, L ;

Kashman, Y ;

Schleyer, M .

TETRAHEDRON, 1997, 53 (47) :16147-16152

[2] HIGH MOLECULAR-WEIGHT POLYACETYLENES FROM PETROSIA-FICIFORMIS - FURTHER STRUCTURAL-ANALYSIS AND BIOLOGICAL-ACTIVITY [J].

CIMINO, G ;

DEGIULIO, A ;

DEROSA, S ;

DIMARZO, V .

TETRAHEDRON LETTERS, 1989, 30 (27) :3563-3566

[3] Triangulynes A-H and triangulynic acid, new cytotoxic polyacetylenes from the marine sponge Pellina triangulata [J].

Dai, JR ;

Hallock, YF ;

Cardellina, JH ;

Gray, GN ;

Boyd, MR .

JOURNAL OF NATURAL PRODUCTS, 1996, 59 (09) :860-865

[4] Vasculyne, a new cytotoxic acetylenic alcohol from the marine sponge Cribrochalina, vasculum [J].

Dai, JR ;

Hallock, YF ;

Cardellina, JH ;

Boyd, MR .

JOURNAL OF NATURAL PRODUCTS, 1996, 59 (01) :88-89

[5] Marine natural products [J].

Faulkner, DJ .

NATURAL PRODUCT REPORTS, 1997, 14 (03) :259-302

[6] New acetylenic metabolites from the marine sponge Pellina triangculata [J].

Fu, X ;

Abbas, SA ;

Schmitz, FJ ;

Vidavsky, I ;

Gross, ML ;

Laney, M ;

Schatzman, RC ;

Cabuslay, RD .

TETRAHEDRON, 1997, 53 (03) :799-814

[7] BIOACTIVE MARINE METABOLITES .20. PETROSYNOL AND PETROSYNONE, ANTIMICROBIAL C30 POLYACETYLENES FROM THE MARINE SPONGE PETROSIA SP - DETERMINATION OF THE ABSOLUTE-CONFIGURATION [J].

FUSETANI, N ;

SHIRAGAKI, T ;

MATSUNAGA, S ;

HASHIMOTO, K .

TETRAHEDRON LETTERS, 1987, 28 (37) :4313-4314

[8] BIOACTIVE MARINE METABOLITES .21. H,K-ATPASE INHIBITORS FROM THE MARINE SPONGE SIPHONOCHALINA-TRUNCATA - ABSOLUTE-CONFIGURATION OF SIPHONODIOL AND 2 RELATED METABOLITES [J].

FUSETANI, N ;

SUGANO, M ;

MATSUNAGA, S ;

HASHIMOTO, K .

TETRAHEDRON LETTERS, 1987, 28 (37) :4311-4312

[9]

GOU Y, 1994, TETRAHEDRON, V50, P13261

[10] Antitumor activity and stereochemistry of acetylenic alcohols from the sponge Cribrochalina vasculum [J].

Hallock, YF ;

Cardellina, JH ;

Blaschak, MS ;

Alexander, MR ;

Prather, TR ;

Shoemaker, RH ;

Boyd, MR .

JOURNAL OF NATURAL PRODUCTS, 1995, 58 (12) :1801-1807