Optically active amines via lipase-catalyzed methoxyacetylation

被引：138

作者：

Balkenhohl, F

Ditrich, K

Hauer, B

Ladner, W

机构：

来源：

JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG | 1997年 / 339卷 / 04期

关键词：

D O I：

10.1002/prac.19973390166

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Racemic amines can be efficiently resolved using ethylmethoxyacetate as acylating agent in a lipase-catalyzed reaction. The reaction of 1-phenyethylamine with ethylmethoxyacetate in the presence of a lipase from Burkholderia plantarii is presented. Excellent yields and selectivity and minimal amount of enzyme characterize this new process.

引用

页码：381 / 384

页数：4

共 42 条

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