Pseudomonas cepacia lipase mediated amidation of benzyl esters

被引：23

作者：

Adamczyk, M

Grote, J

机构：

[1] Department of Chemistry (D9NM), Abbott Diagnostics Division, Abbott Laboratories, Abbott Park, IL 60064-3500

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 44期

关键词：

D O I：

10.1016/0040-4039(96)01792-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Although lipases have been known for some time as catalysts useful for regioselective transesterification or hydrolysis, studies regarding their use as ester amidation catalysts are limited. We have found that the lipase from Pseudomonas cepacia catalyzes amidation reactions with benzyl esters, producing high yields of amides with a variety of different amines. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：7913 / 7916

页数：4

共 26 条

[1] LIPASE-MEDIATED HYDROLYSIS OF RAPAMYCIN 42-HEMISUCCINATE BENZYL AND METHYL-ESTERS [J].

ADAMCZYK, M ;

GEBLER, JC ;

MATTINGLY, PG .

TETRAHEDRON LETTERS, 1994, 35 (07) :1019-1022

[2] CHEMOENZYMATIC TRANSFORMATIONS OF SENSITIVE SYSTEMS - PREPARATION OF DIGOXIGENIN HAPTENS VIA REGIOSELECTIVE LIPASE-MEDIATED HYDROLYSIS [J].

ADAMCZYK, M ;

GEBLER, JC ;

GROTE, J .

TETRAHEDRON LETTERS, 1995, 36 (39) :6987-6990

[3] UNEXPECTEDLY FACILE HYDROLYSIS OF DIGOXIN ESTERS - THE IMPORTANCE OF APPROPRIATE CONTROLS IN LIPASE-MEDIATED HYDROLYSIS [J].

ADAMCZYK, M ;

GEBLER, JC ;

GROTE, J .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (11) :3557-3560

[4]

ASTORGA C, 1994, J CHEM SOC P1, P826

[5] REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF THE CANDIDA-ANTARCTICA LIPASE-CATALYZED AMIDATIONS OF CBZ-L-GLUTAMIC AND CBZ-D-GLUTAMIC ACID DIESTERS [J].

CHAMORRO, C ;

GONZALEZMUNIZ, R ;

CONDE, S .

TETRAHEDRON-ASYMMETRY, 1995, 6 (09) :2343-2352

[6] ENZYMATIC CATALYSIS IN MONOPHASIC ORGANIC-SOLVENTS [J].

DORDICK, JS .

ENZYME AND MICROBIAL TECHNOLOGY, 1989, 11 (04) :194-211

[7]

FABER K, 1992, SYNTHESIS-STUTTGART, P895

[8]

FANG JM, 1994, SYNLETT, P393

[9] LIPASE-CATALYZED AMINOLYSIS AND AMMONOLYSIS OF BETA-KETOESTERS - SYNTHESIS OF OPTICALLY-ACTIVE BETA-KETOAMIDES [J].

GARCIA, MJ ;

REBOLLEDO, F ;

GOTOR, V .

TETRAHEDRON, 1994, 50 (23) :6935-6940

[10]

GARCIA MJ, 1993, TETRAHEDRON-ASYMMETR, V4, P2199

← 1 2 3 →