Facile access to N-thiazolyl α-amino acids from α-bromo ketones and α-amino acids

被引：33

作者：

Rudolph, J ^{[1
]}

机构：

[1] Bayer AG, Cent Res, Chem Life Sci, D-51368 Leverkusen, Germany

来源：

TETRAHEDRON | 2000年 / 56卷 / 20期

关键词：

thiazoles; amines; amino acids and derivatives; thiocyanates;

D O I：

10.1016/S0040-4020(00)00190-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Substituted 2-aminothiazoles are synthesized in a one-pot procedure using readily available alpha-bromo ketones and amines. This method is compatible with a wide range of functional groups and offers a facile and efficient access to the class of N-thiazolyl alpha-amino acid derivatives. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3161 / 3165

页数：5

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