Catalytic promiscuity in biomimetic systems: Catecholase-like activity, phosphatase-like activity, and hydrolytic DNA cleavage promoted by a new dicopper(II) hydroxo-bridged complex

被引:179
作者
Rey, Nicolas A.
Neves, Ademir [1 ]
Bortoluzzi, Adailton J.
Pich, Claus T.
Terenzi, Hernan
机构
[1] Univ Fed Santa Catarina, Dept Quim, Lab Bioinorgan & Cristalog, BR-88040900 Florianopolis, SC, Brazil
[2] Univ Fed Santa Catarina, Dept Bioquim, Lab Expressao Genica, CCB, BR-88040900 Florianopolis, SC, Brazil
关键词
D O I
10.1021/ic0613107
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Presented in this Communication are the structure, physicochemical properties, and catalytic promiscuity of a new dinuclear Cu-II(mu-OH)Cu-II complex containing a novel N,O-donor symmetric dinucleating ligand.
引用
收藏
页码:348 / 350
页数:3
相关论文
共 18 条
[1]   SYNTHESIS, STRUCTURE, AND SPECTROSCOPIC PROPERTIES OF COPPER(II) COMPOUNDS CONTAINING NITROGEN SULFUR DONOR LIGANDS - THE CRYSTAL AND MOLECULAR-STRUCTURE OF AQUA[1,7-BIS(N-METHYLBENZIMIDAZOL-2'-YL)-2,6-DITHIAHEPTANE]COPPER(II) PERCHLORATE [J].
ADDISON, AW ;
RAO, TN ;
REEDIJK, J ;
VANRIJN, J ;
VERSCHOOR, GC .
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1984, (07) :1349-1356
[2]   [Gd-AAZTA]-:: A new structural entry for an improved generation of MRI contrast agents [J].
Aime, S ;
Calabi, L ;
Cavallotti, C ;
Gianolio, E ;
Giovenzana, GB ;
Losi, P ;
Maiocchi, A ;
Palmisano, G ;
Sisti, M .
INORGANIC CHEMISTRY, 2004, 43 (24) :7588-7590
[3]   Dicopper(II) complexes of H-BPMP-type ligands:: pH-induced changes of redox, spectroscopic (19F NMR studies of fluorinated complexes), structural properties, and catecholase activities [J].
Belle, C ;
Beguin, C ;
Gautier-Luneau, I ;
Hamman, S ;
Philouze, C ;
Pierre, JL ;
Thomas, F ;
Torelli, S .
INORGANIC CHEMISTRY, 2002, 41 (03) :479-491
[4]   Synthesis of a flexible ligand for assembling two metal ions in close proximity. Crystal structures of binuclear nickel and copper complexes [J].
Dapporto, P ;
Formica, M ;
Fusi, V ;
Micheloni, M ;
Paoli, P ;
Pontellini, R ;
Rossi, P .
INORGANIC CHEMISTRY, 2000, 39 (20) :4663-4665
[5]   THE SYNTHESIS, REDOX PROPERTIES, AND LIGAND-BINDING OF HETEROBINUCLEAR TRANSITION-METAL MACROCYCLIC LIGAND COMPLEXES - MEASUREMENT OF AN APPARENT DELOCALIZATION ENERGY IN A MIXED-VALENT CUICUII COMPLEX [J].
GAGNE, RR ;
SPIRO, CL ;
SMITH, TJ ;
HAMANN, CA ;
THIES, WR ;
SHIEMKE, AK .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (14) :4073-4081
[6]  
Kannappan R, 2003, P INDIAN AS-CHEM SCI, V115, P1
[7]   Enhancing catalytic promiscuity for biocatalysis [J].
Kazlauskas, RJ .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2005, 9 (02) :195-201
[8]   Crystal structure of a plant catechol oxidase containing a dicopper center [J].
Klabunde, T ;
Eicken, C ;
Sacchettini, JC ;
Krebs, B .
NATURE STRUCTURAL BIOLOGY, 1998, 5 (12) :1084-1090
[9]   DNA hydrolysis promoted by di- and multi-nuclear metal complexes [J].
Liu, CL ;
Wang, M ;
Zhang, TL ;
Sun, HZ .
COORDINATION CHEMISTRY REVIEWS, 2004, 248 (1-2) :147-168
[10]   The catalytic mechanisms of binuclear metallohydrolases [J].
Mitic, Natasa ;
Smith, Sarah J. ;
Neves, Ademir ;
Guddat, Luke W. ;
Gahan, Lawrence R. ;
Schenk, Gerhard .
CHEMICAL REVIEWS, 2006, 106 (08) :3338-3363