The Rotterdam Study: 2010 objectives and design update

被引：222

作者：

Hofman, Albert ^{[1
]}

Breteler, Monique M. B. ^{[1
]}

Duijn, Cornelia M. van ^{[1
]}

Janssen, Harry L. A. ^{[2
]}

Krestin, Gabriel P. ^{[3
]}

Kuipers, Ernst J. ^{[2
]}

Stricker, Bruno H. Ch. ^{[1
,2
]}

Tiemeier, Henning ^{[1
]}

Uitterlinden, Andre G. ^{[1
,2
]}

Vingerling, Johannes R. ^{[1
,4
]}

Witteman, Jacqueline C. M. ^{[1
]}

机构：

[1] Erasmus MC, Dept Epidemiol, NL-3000 CA Rotterdam, Netherlands

[2] Erasmus MC, Dept Internal Med, NL-3000 CA Rotterdam, Netherlands

[3] Erasmus MC, Dept Radiol, NL-3000 CA Rotterdam, Netherlands

[4] Erasmus MC, Dept Ophthalmol, NL-3000 CA Rotterdam, Netherlands

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 2009年 / 24卷 / 09期

关键词：

Biomarkers; Cardiovascular diseases; Cohort study; Endocrine diseases; Epidemiologic methods; Genetic epidemiology; Liver diseases; Neurological diseases; Ophthalmic diseases; Pharmacoepidemiology; Psychiatric diseases; Respiratory diseases; BONE-MINERAL DENSITY; C-REACTIVE PROTEIN; AGE-RELATED MACULOPATHY; RETINAL VESSEL DIAMETERS; GENOME-WIDE ASSOCIATION; CORONARY-HEART-DISEASE; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PHYSICAL-ACTIVITY QUESTIONNAIRE; CARDIOVASCULAR RISK-FACTORS; AGING MACULA DISORDER;

D O I：

10.1007/s10654-009-9386-z

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in close to a 1,000 research articles and reports (see http://www.epib.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.

引用

页码：553 / 572

页数：20

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