Current status of hepatitis G virus (GBV-C) in transfusion: Is it relevant?

被引:18
作者
Karayiannis, P
Thomas, HC
机构
[1] Department of Medicine, Imp. Coll. Sch. Med. at St. Mary's, London
[2] Department of Medicine, ICSM SM, London W2 1NY, South Wharf Road
基金
美国能源部;
关键词
D O I
10.1046/j.1423-0410.1997.7320063.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A new flavivirus, provisionally designated hepatitis G virus or GBV-C has recently been described. The virus is parenterally transmitted by exposure to blood through transfusion, intravenous drug use and haemodialysis. Heat-or chemically-treated blood products are associated with reduced risk of infection. The virus may also be transmitted from mother to infant and by the sexual route. Although hepatitis G virus has been detected in patients with acute and chronic hepatitis, a causative role of the virus in such cases has not been established. The majority of long term carriers of the virus appear to have no liver, biochemical or histological abnormalities.
引用
收藏
页码:63 / 69
页数:7
相关论文
共 65 条
[61]  
3.0.CO
[62]  
2-8
[63]   A prospective study of transfusion-transmitted GB virus C infection: Similar frequency but different clinical presentation compared with hepatitis C virus [J].
Wang, JT ;
Tsai, FC ;
Lee, CZ ;
Chen, PJ ;
Sheu, JC ;
Wang, TH ;
Chen, DS .
BLOOD, 1996, 88 (05) :1881-1886
[64]   DETECTION OF THE GBV-C HEPATITIS-VIRUS GENOME IN SERUM FROM PATIENTS WITH FULMINANT-HEPATITIS OF UNKNOWN ETIOLOGY [J].
YOSHIBA, M ;
OKAMOTO, H ;
MISHIRO, S .
LANCET, 1995, 346 (8983) :1131-1132
[65]   Aplastic anaemia after HGV infection [J].
Zaidi, Y ;
Chapman, CS ;
Myint, S .
LANCET, 1996, 348 (9025) :471-472