DICER-LIKE1:: blind men and elephants in Arabidopsis development

被引:367
作者
Schauer, SE
Jacobsen, SE
Meinke, DW
Ray, A
机构
[1] Univ Rochester, Dept Biol, Rochester, NY 14627 USA
[2] Univ Calif Los Angeles, Dept Mol Cellular & Dev Biol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
[4] Oklahoma State Univ, Dept Bot, Stillwater, OK 74078 USA
[5] Keck Grad Inst, Claremont, CA 91711 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/S1360-1385(02)02355-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Genetic studies of embryo, ovule and flower development in Arabidopsis thaliana have led to the independent isolation of different mutant alleles of a single gene (SIN1/SUS1/CAF, now renamed DCL1) that encodes a complex RNA-processing enzyme. DCL1 shows similarity to the Dicer group of genes, which are required for RNA silencing in Drosophila and Caenorhabditis. These recent findings identify a novel but conserved mechanism of post-transcriptional gene regulation that is important for development in eukaryotes.
引用
收藏
页码:487 / 491
页数:5
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