DICER-LIKE1:: blind men and elephants in Arabidopsis development

被引:367
作者
Schauer, SE
Jacobsen, SE
Meinke, DW
Ray, A
机构
[1] Univ Rochester, Dept Biol, Rochester, NY 14627 USA
[2] Univ Calif Los Angeles, Dept Mol Cellular & Dev Biol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
[4] Oklahoma State Univ, Dept Bot, Stillwater, OK 74078 USA
[5] Keck Grad Inst, Claremont, CA 91711 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/S1360-1385(02)02355-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Genetic studies of embryo, ovule and flower development in Arabidopsis thaliana have led to the independent isolation of different mutant alleles of a single gene (SIN1/SUS1/CAF, now renamed DCL1) that encodes a complex RNA-processing enzyme. DCL1 shows similarity to the Dicer group of genes, which are required for RNA silencing in Drosophila and Caenorhabditis. These recent findings identify a novel but conserved mechanism of post-transcriptional gene regulation that is important for development in eukaryotes.
引用
收藏
页码:487 / 491
页数:5
相关论文
共 40 条
[21]  
LANG JD, 1994, GENETICS, V137, P1101
[22]   Endogenous and silencing-associated small RNAs in plants [J].
Llave, C ;
Kasschau, KD ;
Rector, MA ;
Carrington, JC .
PLANT CELL, 2002, 14 (07) :1605-1619
[23]   Arabidopsis cyt1 mutants are deficient in a mannose-1-phosphate guanylyltransferase and point to a requirement of N-linked glycosylation for cellulose biosynthesis [J].
Lukowitz, W ;
Nickle, TC ;
Meinke, DW ;
Last, RL ;
Conklin, PL ;
Somerville, CR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (05) :2262-2267
[24]  
Lynn K, 1999, DEVELOPMENT, V126, P469
[25]   RNA: Guiding gene silencing [J].
Matzke, M ;
Matzke, AJM ;
Kooter, JM .
SCIENCE, 2001, 293 (5532) :1080-1083
[26]  
McElver J, 2001, GENETICS, V159, P1751
[27]   Community standards: A new series of guidelines for plant science - Community standards for Arabidopsis genetics [J].
Meinke, D ;
Koornneef, M .
PLANT JOURNAL, 1997, 12 (02) :247-253
[28]   Transcriptional silencing and promoter methylation triggered by double-stranded RNA [J].
Mette, MF ;
Aufsatz, W ;
van der Winden, J ;
Matzke, MA ;
Matzke, AJM .
EMBO JOURNAL, 2000, 19 (19) :5194-5201
[29]   The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation [J].
Olsen, PH ;
Ambros, V .
DEVELOPMENTAL BIOLOGY, 1999, 216 (02) :671-680
[30]  
Prigge MJ, 2001, PLANT CELL, V13, P1263, DOI 10.1105/tpc.13.6.1263