Conformational control of transmembrane Cl- transport

被引：131

作者：

Santacroce, Paul V.

Davis, Jeffery T. ^{[1
]}

Light, Mark E.

Gale, Philip A.

Iglesias-Sanchez, Jose Carlos

Prados, Pilar

Quesada, Roberto

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

[2] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

[3] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1021/ja068067v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Preorganization of the isophthalamide cleft in N,N'-dibutyl-4,6-dihydroxyisophthalamide (2) by means of intramolecular hydrogen bonds results in an enhanced anion receptor that displays significant chloride transport activity into EYPC liposomes. This function is easily switchable by controlling the pH.

引用

收藏

页码：1886 / +

页数：3

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