NMR methods for characterizing microsecond to millisecond dynamics in recognition and catalysis

被引：111

作者：

Akke, M ^{[1
]}

机构：

[1] Lund Univ, Dept Biophys Chem, SE-22100 Lund, Sweden

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2002年 / 12卷 / 05期

关键词：

D O I：

10.1016/S0959-440X(02)00369-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During the past two years, significant advances have been made in the development of NMR methods for studying biomolecular dynamics on the microsecond to millisecond timescale. Applications of these methods to biologically relevant systems have provided compelling evidence that, in many cases, conformational dynamics on these timescales govern the rates of biomolecular recognition and catalysis.

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收藏

页码：642 / 647

页数：6

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