Lignans from Kadsura angustifolia

被引：48

作者：

Chen, YG

Qin, GW ^{[1
]}

Xie, YY

Cheng, KF

Lin, ZW

Sun, HD

Kang, YH

Han, BH

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China

[2] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China

[4] Seoul Natl Univ, Inst Nat Prod Res, Seoul 110460, South Korea

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 1998年 / 1卷 / 02期

关键词：

lignan; Kadsura angustifolia; anti-PAF activities;

D O I：

10.1080/10286029808039854

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds 2 and 5 showed moderate platelet-activating factor (PAF) antagonistic activities with IC50 values of 2.6 x 10(-5) and 4.1 x 10(-5) M, respectively.

引用

页码：125 / 131

页数：7

共 11 条

[1]

CHEN YG, 1998, IN PRESS PHYTOCHEMIS, V47

[2]

CHEN YY, 1976, SCI SINICA, V19, P276

[3]

IKEYA Y, 1979, CHEM PHARM BULL, V27, P1383

[4] Four new C19 homolignans, schiarisanrins A, B, and D and cytotoxic schiarisanrin C, from Schizandra arisanensis [J].