Immunoassays for aflatoxins

被引：218

作者：

Li, Peiwu ^{[1
]}

Zhang, Qi ^{[1
]}

Zhang, Wen ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Oil Crops Res Inst, Dept Qual Stand & Food Safety, Wuhan 430062, Peoples R China

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2009年 / 28卷 / 09期

基金：

美国国家科学基金会;

关键词：

Aflatoxin; Agricultural product; Antibody; Hapten; Immunoassay; Immunogen; Immunosensor; Nanoparticle label; Non-competitive assay; MOLECULARLY IMPRINTED POLYMERS; LINKED-IMMUNOSORBENT-ASSAY; ELECTROCHEMICAL IMMUNOSENSOR; MONOCLONAL-ANTIBODIES; ENZYME-IMMUNOASSAY; COMPETITIVE ELISA; M1; DETERMINATION; RAPID DETECTION; QUANTUM DOTS; OCHRATOXIN-A;

D O I：

10.1016/j.trac.2009.07.003

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Immunoassays for aflatoxin analysis have been regarded as valuable supplements to existing and rapidly developing chromatographic techniques. We describe six types of aflatoxin immunogens and their characteristics, reported antibodies against aflatoxins, traditional and novel labeled materials for assay signaling, three immunoassay formats, assay devices (e.g., microtiter plate and reader, lateral flow strip, electronic and optical immunosensors, and a rapid tester dedicated to aflatoxins) and applications of immunoassay in agricultural products. We show trends towards sensitivity, simplification, intelligence and portability. After setting out five challenges in developing immunoassays, we predict that techniques involving novel nanoparticle labels and non-competitive assay may become the main trends in research and that immunoassay devices will be used in many fields. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1115 / 1126

页数：12

共 84 条

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