Alumina supported-CeCl3•7H2O-NaI:: an efficient catalyst for the cyclization f 2′-aminochalcones to the corresponding 2-aryl-2,3-dihydroquinolin-4(1H)-ones under solvent free conditions

被引：69

作者：

Ahmed, Naseem ^{[1
]}

van Lier, Johan E. ^{[1
]}

机构：

[1] Univ Sherbrooke, Fac Med & Hlth Sci, Dept Med Nucl & Radiobiol, Sherbrooke, PQ J1H 5N4, Canada

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 01期

基金：

加拿大健康研究院;

关键词：

alumina and silica gel supported-CeCl3 center dot 7H(2)O-NaI; 2 '-aminochalcones; Aza-Michael reaction; 2-aryl-2,3-dihydroquinolin-4(1H)-ones;

D O I：

10.1016/j.tetlet.2006.11.020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We recently advanced silica gel supported-TaBr5 as an efficient catalyst for the isomerization of 2'-aminochalcones to the corresponding 2-aryl-2,3-dihydroquinolin-4(1H)-ones under solvent free conditions (Tetrahedron Lett. 2006, 47, 2725-2729). This conversion can be further improved through the use of more economic alumina supported-CeCl3 center dot 7H(2)O-NaI, providing high yields of up to 98% at lower reaction temperatures. This stable catalyst is easily prepared, active under solvent-free conditions and employed under environmentally friendly conditions. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：13 / 15

页数：3

共 22 条

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