Low catalyst loading ligand-free palladium-catalyzed direct arylation of furans: an economically and environmentally attractive access to 5-arylfurans

被引：95

作者：

Dong, Jia Jia ^{[1
]}

Roger, Julien ^{[1
]}

Pozgan, Franc ^{[2
]}

Doucet, Henri ^{[1
]}

机构：

[1] Univ Rennes 1, CNRS, Inst Sci Chim Rennes, UMR Catalyse & Organomet 6226, F-35042 Rennes, France

[2] Univ Ljubljana, Fac Chem & Chem Technol, SI-1000 Ljubljana, Slovenia

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 11期

关键词：

DIRECT C-2 ARYLATION; INCLUDING FREE (NH)-IMIDAZOLE; C-H FUNCTIONALIZATION; REGIOSELECTIVE SYNTHESIS; HETEROARYL HALIDES; ARYLBORONIC ACIDS; ROOM-TEMPERATURE; ARYL CHLORIDES; HECK REACTIONS; DERIVATIVES;

D O I：

10.1039/b915290n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The direct 5-arylation of furans at very low catalyst loading using Pd(OAc)(2) as catalyst without added ligand proceed in high yields. Turnover numbers up to 10000 have been obtained for the coupling of several activated aryl bromides. A wide range of functions on the furan or aryl bromide is tolerated.

引用

页码：1832 / 1846

页数：15

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