Solid-phase synthesis of C-terminal thio-linked glycopeptides

被引：15

作者：

Malkinson, JP ^{[1
]}

Falconer, RA ^{[1
]}

机构：

[1] Univ London, Sch Pharm, Dept Pharmaceut & Biol Chem, London WC1N 1AX, England

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(02)02419-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A solid-phase Mitsunobu reaction between a resin-bound 1-thiosugar and an N-Fmoc protected amino alcohol was successfully employed for thio-linked glycopeptide synthesis. Facile cleavage and deprotection in one step afforded the target glycopeptide in good yield and purity. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：9549 / 9552

页数：4

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