The impact of genomics on the exploitation of the myxobacterial secondary metabolome

被引:77
作者
Wenzel, Silke C. [1 ]
Mueller, Rolf [1 ]
机构
[1] Univ Saarland, Inst Pharmaceut Biotechnol, D-66041 Saarbrucken, Germany
关键词
BIOSYNTHETIC GENE-CLUSTER; RIBOSOMAL PEPTIDE SYNTHETASE; STRAIN SORANGIUM-CELLULOSUM; POLYKETIDE ANTIBIOTIC TA; MARINER-BASED TRANSPOSON; AURANTIACA SG A15; STIGMATELLA-AURANTIACA; HETEROLOGOUS EXPRESSION; MYXOCOCCUS-XANTHUS; STRUCTURE ELUCIDATION;
D O I
10.1039/b817073h
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Myxobacteria are one of the most outstanding resources for microbial natural products. This review focuses on the impact of genomics on the evaluation and exploitation of their biosynthetic potential.
引用
收藏
页码:1385 / 1407
页数:23
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