Absence of germline mutations in genes within the MAP kinase pathway in familial non-medullary thyroid cancer

被引:13
作者
Hou, Peng [1 ]
Xing, Mingzhao [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Div Endocrinol & Metab, Dept Med, Baltimore, MD 21287 USA
关键词
Germline mutations; MAP Kinase pathway; BRAF gene; RAS genes; MEK genes; single nucleotide polymorphisms; Familial nonmedullary thyroid cancer (FNMTC);
D O I
10.4161/cc.5.17.3190
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:2036 / 2039
页数:4
相关论文
共 21 条
[1]   Familial nonmedullary thyroid cancer. [J].
Alsanea O. .
Current Treatment Options in Oncology, 2000, 1 (4) :345-351
[2]   Germline mutations in HRAS proto-oncogene cause Costello syndrome [J].
Aoki, Y ;
Niihori, T ;
Kawame, H ;
Kurosawa, K ;
Filocamo, M ;
Kato, K ;
Suzuki, Y ;
Kure, S ;
Matsubara, Y .
NATURE GENETICS, 2005, 37 (10) :1038-1040
[3]   The molecular basis of thyroid epithelial tumorigenesis [J].
Bongarzone, I ;
Pierotti, MA .
TUMORI, 2003, 89 (05) :514-516
[4]   Mutations of the BRAF gene in human cancer [J].
Davies, H ;
Bignell, GR ;
Cox, C ;
Stephens, P ;
Edkins, S ;
Clegg, S ;
Teague, J ;
Woffendin, H ;
Garnett, MJ ;
Bottomley, W ;
Davis, N ;
Dicks, N ;
Ewing, R ;
Floyd, Y ;
Gray, K ;
Hall, S ;
Hawes, R ;
Hughes, J ;
Kosmidou, V ;
Menzies, A ;
Mould, C ;
Parker, A ;
Stevens, C ;
Watt, S ;
Hooper, S ;
Wilson, R ;
Jayatilake, H ;
Gusterson, BA ;
Cooper, C ;
Shipley, J ;
Hargrave, D ;
Pritchard-Jones, K ;
Maitland, N ;
Chenevix-Trench, G ;
Riggins, GJ ;
Bigner, DD ;
Palmieri, G ;
Cossu, A ;
Flanagan, A ;
Nicholson, A ;
Ho, JWC ;
Leung, SY ;
Yuen, ST ;
Weber, BL ;
Siegler, HF ;
Darrow, TL ;
Paterson, H ;
Marais, R ;
Marshall, CJ ;
Wooster, R .
NATURE, 2002, 417 (6892) :949-954
[5]  
GROSSMAN RF, 1995, ARCH SURG-CHICAGO, V130, P892
[6]   The Ras-Raf-MEK-ERK pathway in the treatment of cancer [J].
Hilger, RA ;
Scheulen, ME ;
Strumberg, D .
ONKOLOGIE, 2002, 25 (06) :511-518
[7]   Mapping of a gene predisposing to familial thyroid tumors with cell oxyphilia to chromosome 19 and exclusion of JUN B as a candidate gene [J].
Kraimps, JL ;
Canzian, F ;
Jost, C ;
Menet, E ;
Amati, P ;
Levillian, P ;
Harach, R ;
Lesueur, F ;
Barbier, J ;
Romeo, G ;
Bonneau, D .
SURGERY, 1999, 126 (06) :1188-1194
[8]   Papillary thyroid carcinoma associated with papillary renal neoplasia: genetic linkage analysis of a distinct heritable tumor syndrome [J].
Malchoff, CD ;
Sarfarazi, M ;
Tendler, B ;
Forouhar, F ;
Whalen, G ;
Joshi, V ;
Arnold, A ;
Malchoff, DM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (05) :1758-1764
[9]   The genetics of hereditary nonmedullary thyroid carcinoma [J].
Malchoff, CD ;
Malchoff, DM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (06) :2455-2459
[10]   Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21 [J].
McKay, JD ;
Lesueur, F ;
Jonard, L ;
Pastore, A ;
Williamson, J ;
Hoffman, L ;
Burgess, J ;
Duffield, A ;
Papotti, M ;
Stark, M ;
Sobol, H ;
Maes, B ;
Murat, A ;
Kääriäinen, H ;
Bertholon-Grégoire, M ;
Zini, M ;
Rossing, MA ;
Toubert, ME ;
Bonichon, F ;
Cavarec, M ;
Bernard, AM ;
Boneu, A ;
Leprat, F ;
Haas, O ;
Lasset, C ;
Schlumberger, M ;
Canzian, F ;
Goldgar, DE ;
Romeo, G .
AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (02) :440-446