An efficient, rapid and regioselective nuclear bromination of aromatics and heteroaromatics with NBS using sulfonic-acid-functionalized silica as a heterogeneous recyclable catalyst

被引：77

作者：

Das, Biswanath ^{[1
]}

Venkateswarlu, Katta ^{[1
]}

Krishnaiah, Maddeboina ^{[1
]}

Holla, Harish ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 49期

关键词：

aromatic and heteroaromatic compounds; nuclear bromination; NBS; sulfonic-acid-functionalized silica; regioselectivity; heterogeneous recyclable catalyst;

D O I：

10.1016/j.tetlet.2006.10.029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, efficient and rapid method has been developed for high-yielding regioselective nuclear monobromination of aromatic and heteroaromatic compounds using NBS in the presence of sulfonic-acid-functionalized silica at room temperature. The catalyst works under heterogeneous conditions and can be recycled. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：8693 / 8697

页数：5

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