Systemic antigen in the treatment of T-cell-mediated autoimmune diseases

被引：74

作者：

Liblau, R

Tisch, R

Bercovici, N

McDevitt, HO

机构：

[1] HOP LA PITIE SALPETRIERE,INSERM CJF9608,F-75013 PARIS,FRANCE

[2] UNIV N CAROLINA,DEPT MICROBIOL & IMMUNOL,CHAPEL HILL,NC 27599

[3] STANFORD UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL,STANFORD,CA 94305

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(97)01171-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systemic injection of antigen is one of the approaches that reproducibly induces effective antigen-specific hyporesponsiveness. Here, Roland Liblau and colleagues discuss the cellular and molecular bases of such tolerance, review the current use of this therapeutic strategy in experimental organ-specific autoimmune diseases and analyse what steps are necessary to make this approach suitable for clinical use.

引用

页码：599 / 604

页数：6

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