Proteomics of the peroxisome

被引：35

作者：

Saleem, R. A. ^{[1
]}

Smith, J. J. ^{[1
]}

Aitchison, J. D. ^{[1
]}

机构：

[1] Inst Syst Biol, Seattle, WA 98103 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 2006年 / 1763卷 / 12期

关键词：

peroxisome; proteome; mass spectrometry; protein quantification; protein localization; in silico prediction;

D O I：

10.1016/j.bbamcr.2006.09.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genomes provide us with a blue print for the potential of a cell. However, the activity of a cell is expressed in its proteome. Full understanding of the complexity of cells demands a comprehensive view of the proteome; its interactions, activity states and organization. Comprehensive proteomic approaches applied to peroxisomes have yielded new insights into the organelle and its dynamic interplay with other cellular structures. As technologies and methodologies improve, proteomics hold the promise for new discoveries of peroxisome function and a full description of this dynamic organelle. (c) 2006 Elsevier B.V. All rights reserved.

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收藏

页码：1541 / 1551

页数：11

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