A practical synthesis of betulinic acid

被引：70

作者：

Csuk, Rene ^{[1
]}

Schmuck, Kianga ^{[1
]}

Schaefer, Renate ^{[1
]}

机构：

[1] Univ Halle Wittenberg, Inst f Organ Chem, D-06120 Halle, Germany

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 49期

关键词：

LUPANE TRITERPENES; DERIVATIVES; OXIDATION; AGENTS;

D O I：

10.1016/j.tetlet.2006.10.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

A new synthetic route for the synthesis of betulinic acid from betulin has been developed. The main step of this procedure is the selective oxidation of the primary alcohol function of betulin without affecting the secondary hydroxyl group. Applying shorter reaction times and lower temperatures results in the exclusive formation of the corresponding aldehyde, betulinal. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：8769 / 8770

页数：2

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