Photocleavable Hydrogels for Light-Triggered siRNA Release

被引:54
作者
Cong Truc Huynh [1 ]
Minh Khanh Nguyen [1 ]
Tonga, Gulen Yesilbag [2 ]
Longe, Lionel [2 ,3 ]
Rotello, Vincent M. [2 ]
Alsberg, Eben [1 ,4 ]
机构
[1] Case Western Reserve Univ, Dept Biomed Engn, 10900 Euclid Ave, Cleveland, OH 44106 USA
[2] Univ Massachusetts, Dept Chem, 710 North Pleasant St, Amherst, MA 01003 USA
[3] Ecole Natl Super Chim Biol & Phys, Dept Chim Phys, 16 Ave Pey Berland, F-33607 Pessac, France
[4] Case Western Reserve Univ, Dept Orthopaed Surg, 10900 Euclid Ave, Cleveland, OH 44106 USA
基金
美国国家卫生研究院;
关键词
controlled release; on-demand release; photolabile hydrogels; siRNA; UV-controllable release; SMALL INTERFERING RNAS; PHOTODEGRADABLE HYDROGELS; IN-VIVO; BIODEGRADABLE HYDROGELS; PHOTOREGULATED RELEASE; DELIVERY; NANOPARTICLES; DRUGS; DIFFERENTIATION; THERAPEUTICS;
D O I
10.1002/adhm.201500778
中图分类号
R318 [生物医学工程];
学科分类号
100103 [病原生物学];
摘要
[No abstract available]
引用
收藏
页码:305 / 310
页数:6
相关论文
共 55 条
[1]
Photoregulated Release of Caged Anticancer Drugs from Gold Nanoparticles [J].
Agasti, Sarit S. ;
Chompoosor, Apiwat ;
You, Chang-Cheng ;
Ghosh, Partha ;
Kim, Chae Kyu ;
Rotello, Vincent M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (16) :5728-+
[2]
siRNA Nanoparticle Functionalization of Nanostructured Scaffolds Enables Controlled Multilineage Differentiation of Stem Cells [J].
Andersen, Morten O. ;
Nygaard, Jens V. ;
Burns, Jorge S. ;
Raarup, Merete K. ;
Nyengaard, Jens R. ;
Bunger, Cody ;
Besenbacher, Flemming ;
Howard, Kenneth A. ;
Kassem, Moustapha ;
Kjems, Jorgen .
MOLECULAR THERAPY, 2010, 18 (11) :2018-2027
[3]
Inhibition of respiratory viruses by nasally administered siRNA [J].
Bitko, V ;
Musiyenko, A ;
Shulyayeva, O ;
Barik, S .
NATURE MEDICINE, 2005, 11 (01) :50-55
[4]
RNAi therapeutics: a potential new class of pharmaceutical drugs [J].
Bumcrot, David ;
Manoharan, Muthiah ;
Koteliansky, Victor ;
Sah, Dinah W. Y. .
NATURE CHEMICAL BIOLOGY, 2006, 2 (12) :711-719
[5]
RNA interference by nanofiber-based siRNA delivery system [J].
Cao, Haoqing ;
Jiang, Xu ;
Chai, Chou ;
Chew, Sing Yian .
JOURNAL OF CONTROLLED RELEASE, 2010, 144 (02) :203-212
[6]
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate [J].
Choi, Seok Ki ;
Thomas, Thommey ;
Li, Ming-Hsin ;
Kotlyar, Alina ;
Desai, Ankur ;
Baker, James R., Jr. .
CHEMICAL COMMUNICATIONS, 2010, 46 (15) :2632-2634
[7]
Controlled release of human growth hormone from a biodegradable pH/temperature-sensitive hydrogel system [J].
Cong Truc Huynh ;
Kang, Seong Woo ;
Li, Yi ;
Kim, Bong Sup ;
Lee, Doo Sung .
SOFT MATTER, 2011, 7 (19) :8984-8990
[8]
Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels [J].
Cruise, GM ;
Scharp, DS ;
Hubbell, JA .
BIOMATERIALS, 1998, 19 (14) :1287-1294
[9]
Delivery vehicles for small interfering RNA in vivo [J].
De Fougerolles, Antonin R. .
HUMAN GENE THERAPY, 2008, 19 (02) :125-132
[10]
Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing [J].
Dunn, Stuart S. ;
Tian, Shaomin ;
Blake, Steven ;
Wang, Jin ;
Galloway, Ashley L. ;
Murphy, Andrew ;
Pohlhaus, Patrick D. ;
Rolland, Jason P. ;
Napier, Mary E. ;
DeSimone, Joseph M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (17) :7423-7430