Purealidin S and purpuramine J, bromotyrosine alkaloids from the Fijian marine sponge Druinella sp.

被引：39

作者：

Tabudravu, JN ^{[1
]}

Jaspers, M ^{[1
]}

机构：

[1] Univ Aberdeen, Dept Chem, Marine Nat Prod Lab, Aberdeen AB24 3UE, Scotland

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 12期

关键词：

D O I：

10.1021/np020275n

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

引用

页码：1798 / 1801

页数：4

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