Antibody discovery:: phage display

被引：96

作者：

Kretzschmar, T ^{[1
]}

von Rüden, T ^{[1
]}

机构：

[1] MorphoSys AG, D-82152 Martinsried, Germany

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 06期

关键词：

D O I：

10.1016/S0958-1669(02)00380-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Phage display has proven to be a robust and convenient technology for the selection of high-quality human antibodies from diverse libraries. Besides enabling the identification of antibodies in a fast, high-throughput mode, which allows comprehensive protein expression analyses, phage display has been used to identify a fully human therapeutic antibody presently undergoing the regulatory process for market approval.

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页码：598 / 602

页数：5

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