Illumina universal bead arrays

被引：219

作者：

Fan, Jian-Bing ^{[1
]}

Gunderson, Kevin L. ^{[1
]}

Bibikova, Marina ^{[1
]}

Yeakley, Joanne M. ^{[1
]}

Chen, Jing ^{[1
]}

Wickham Garcia, Eliza ^{[1
]}

Lebruska, Lori L. ^{[1
]}

Laurent, Marc ^{[1
]}

Shen, Richard ^{[1
]}

Barker, David ^{[1
]}

机构：

[1] Illumina Inc, San Diego, CA USA

来源：

DNA MICROARRAYS PART A: ARRAY PLATFORMS AND WET-BENCH PROTOCOLS | 2006年 / 410卷

关键词：

D O I：

10.1016/S0076-6879(06)10003-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This chapter describes an accurate, scalable, and flexible microarray technology. It includes a miniaturized array platform where each individual feature is quality controlled and a versatile assay that can be adapted for various genetic analyses, such as single nucleotide polymorphism genotyping, DNA methylation detection, and gene expression profiling. This chapter describes the concept of the BeadArray technology, two different Array of Arrays formats, the assay scheme and protocol, the performance of the system, and its use in large-scale genetic, epigenetic, and expression studies.

引用

页码：57 / +

页数：20

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