The molecular and genetic basis of AD: The end of the beginning - The 2000 Wartenberg lecture

被引:118
作者
Rosenberg, RN [1 ]
机构
[1] Univ Texas, SW Med Ctr, Dept Neurol, Dallas, TX 75390 USA
关键词
D O I
10.1212/WNL.54.11.2045
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:2045 / 2054
页数:10
相关论文
共 107 条
[61]   Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline [J].
Näslund, J ;
Haroutunian, V ;
Mohs, R ;
Davis, KL ;
Davies, P ;
Greengard, P ;
Buxbaum, JD .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (12) :1571-1577
[62]  
Nicoll JAR, 2000, ANN NEUROL, V47, P365, DOI 10.1002/1531-8249(200003)47:3<365::AID-ANA13>3.3.CO
[63]  
2-7
[64]   GENETIC ASSOCIATION OF THE VERY-LOW-DENSITY LIPOPROTEIN (VLDL) RECEPTOR GENE WITH SPORADIC ALZHEIMERS-DISEASE [J].
OKUIZUMI, K ;
ONODERA, O ;
NAMBA, Y ;
IKEDA, K ;
YAMAMOTO, T ;
SEKI, K ;
UEKI, A ;
NANKO, S ;
TANAKA, H ;
TAKAHASHI, H ;
OYANAGI, K ;
MIZUSAWA, H ;
KANAZAWA, I ;
TSUJI, S .
NATURE GENETICS, 1995, 11 (02) :207-209
[65]   Amyloid precursor protein gene isoforms in Alzheimer's disease and other neurodegenerative disorders [J].
Panegyres, PK ;
Zafiris-Toufexis, K ;
Kakulas, BA .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2000, 173 (02) :81-92
[66]   Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration [J].
Patrick, GN ;
Zukerberg, L ;
Nikolic, M ;
de la Monte, S ;
Dikkes, P ;
Tsai, LH .
NATURE, 1999, 402 (6762) :615-622
[67]   Alzheimer's disease and apolipoprotein E-4 allele in an Amish population [J].
PericakVance, MA ;
Johnson, CC ;
Rimmler, JB ;
Saunders, AM ;
Robinson, LC ;
DHondt, EG ;
Jackson, CE ;
Haines, JL .
ANNALS OF NEUROLOGY, 1996, 39 (06) :700-704
[68]  
PODLISNY MB, 1991, AM J PATHOL, V138, P1423
[69]   Tau is a candidate gene for chromosome 17 frontotemporal dementia [J].
Poorkaj, P ;
Bird, TD ;
Wijsman, E ;
Nemens, E ;
Garruto, RM ;
Anderson, L ;
Andreadis, A ;
Wiederholt, WC ;
Raskind, M ;
Schellenberg, GD .
ANNALS OF NEUROLOGY, 1998, 43 (06) :815-825
[70]   Alzheimer's disease: Genetic studies and transgenic models [J].
Price, DL ;
Tanzi, RE ;
Borchelt, DR ;
Sisodia, SS .
ANNUAL REVIEW OF GENETICS, 1998, 32 :461-493