The molecular and genetic basis of AD: The end of the beginning - The 2000 Wartenberg lecture

被引：118

作者：

Rosenberg, RN ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Neurol, Dallas, TX 75390 USA

来源：

NEUROLOGY | 2000年 / 54卷 / 11期

关键词：

D O I：

10.1212/WNL.54.11.2045

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

[No abstract available]

引用

页码：2045 / 2054

页数：10

共 107 条

[81] Neuroscience - Alzheimer's disease: Genotypes, phenotype, and treatments [J].

Selkoe, DJ .

SCIENCE, 1997, 275 (5300) :630-631

[82]

SELKOE DJ, 1998, BLUE BOOK PRACT NEUR, V19, P257

[83] CLONING OF A GENE BEARING MISSENSE MUTATIONS IN EARLY-ONSET FAMILIAL ALZHEIMERS-DISEASE [J].

SHERRINGTON, R ;

ROGAEV, EI ;

LIANG, Y ;

ROGAEVA, EA ;

LEVESQUE, G ;

IKEDA, M ;

CHI, H ;

LIN, C ;

LI, G ;

HOLMAN, K ;

TSUDA, T ;

MAR, L ;

FONCIN, JF ;

BRUNI, AC ;

MONTESI, MP ;

SORBI, S ;

RAINERO, I ;

PINESSI, L ;

NEE, L ;

CHUMAKOV, I ;

POLLEN, D ;

BROOKES, A ;

SANSEAU, P ;

POLINSKY, RJ ;

WASCO, W ;

DASILVA, HAR ;

HAINES, JL ;

PERICAKVANCE, MA ;

TANZI, RE ;

ROSES, AD ;

FRASER, PE ;

ROMMENS, JM ;

STGEORGEHYSLOP, PH .

NATURE, 1995, 375 (6534) :754-760

[84] Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons [J].

Simons, M ;

Keller, P ;

De Strooper, B ;

Beyreuther, K ;

Dotti, CG ;

Simons, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :6460-6464

[85] Purification and cloning of amyloid precursor protein β-secretase from human brain [J].

Sinha, S ;

Anderson, JP ;

Barbour, R ;

Basi, GS ;

Caccavello, R ;

Davis, D ;

Doan, M ;

Dovey, HF ;

Frigon, N ;

Hong, J ;

Jacobson-Croak, K ;

Jewett, N ;

Keim, P ;

Knops, J ;

Lieberburg, I ;

Power, M ;

Tan, H ;

Tatsuno, G ;

Tung, J ;

Schenk, D ;

Seubert, P ;

Suomensaari, SM ;

Wang, SW ;

Walker, D ;

Zhao, J ;

McConlogue, L ;

John, V .

NATURE, 1999, 402 (6761) :537-540

[86] β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis:: Implications for Alzheimer's therapy [J].

Soto, C ;

Sigurdsson, EM ;

Morelli, L ;

Kumar, RA ;

Castano, EM ;

Frangione, B .

NATURE MEDICINE, 1998, 4 (07) :822-826

[87]

St George-Hyslop PH, 1999, NATURE, V400, P116

[88] THE GENETIC-DEFECT CAUSING FAMILIAL ALZHEIMERS-DISEASE MAPS ON CHROMOSOME-21 [J].

STGEORGEHYSLOP, PH ;

TANZI, RE ;

POLINSKY, RJ ;

HAINES, JL ;

NEE, L ;

WATKINS, PC ;

MYERS, RH ;

FELDMAN, RG ;

POLLEN, D ;

DRACHMAN, D ;

GROWDON, J ;

BRUNI, A ;

FONCIN, JF ;

SALMON, D ;

FROMMELT, P ;

AMADUCCI, L ;

SORBI, S ;

PIACENTINI, S ;

STEWART, GD ;

HOBBS, WJ ;

CONNEALLY, PM ;

GUSELLA, JF .

SCIENCE, 1987, 235 (4791) :885-890

[89] BINDING OF HUMAN APOLIPOPROTEIN-E TO SYNTHETIC AMYLOID-BETA PEPTIDE - ISOFORM-SPECIFIC EFFECTS AND IMPLICATIONS FOR LATE-ONSET ALZHEIMER-DISEASE [J].

STRITTMATTER, WJ ;

WEISGRABER, KH ;

HUANG, DY ;

DONG, LM ;

SALVESEN, GS ;

PERICAKVANCE, M ;

SCHMECHEL, D ;

SAUNDERS, AM ;

GOLDGABER, D ;

ROSES, AD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (17) :8098-8102

[90] APOLIPOPROTEIN-E - HIGH-AVIDITY BINDING TO BETA-AMYLOID AND INCREASED FREQUENCY OF TYPE-4 ALLELE IN LATE-ONSET FAMILIAL ALZHEIMER-DISEASE [J].

STRITTMATTER, WJ ;

SAUNDERS, AM ;

SCHMECHEL, D ;

PERICAKVANCE, M ;

ENGHILD, J ;

SALVESEN, GS ;

ROSES, AD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (05) :1977-1981

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