Phytochemistry and biological activities of Phlomis species

被引：125

作者：

Amor, Ilef Limem-Ben ^{[1
,2
]}

Boubaker, Jihed ^{[1
,2
]}

Sgaier, Mohamed Ben ^{[1
,2
]}

Skandrani, Ines ^{[1
,2
]}

Bhouri, Wissem ^{[1
,2
]}

Neffati, Aicha ^{[1
,2
]}

Kilani, Soumaya ^{[1
,2
]}

Bouhlel, Ines ^{[1
,2
]}

Ghedira, Kamel ^{[1
,2
]}

Chekir-Ghedira, Leila ^{[1
,2
]}

机构：

[1] Fac Med Dent, Cellular & Mol Biol Lab, Monastir 5019, Tunisia

[2] Fac Pharm, Unity Pharmacognosy Mol Biol 99 UR 07 03, Monastir 5000, Tunisia

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2009年 / 125卷 / 02期

关键词：

Phlomis; Lamiaceae; Secondary metabolites; Ethnobotanical uses; Pharmacological properties; ESSENTIAL OIL COMPOSITION; ENOYL-ACP REDUCTASE; PHENYLETHANOID GLYCOSIDES; CHEMICAL-COMPOSITION; IRIDOID GLUCOSIDES; MEDICINAL-PLANTS; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANISODONTA BOISS; OLIVIERI BENTH;

D O I：

10.1016/j.jep.2009.06.022

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The genus Phlomis L belongs to the Lamiaceae family and encompasses 100 species native to Turkey, North Africa, Europe and Asia. It is a popular herbal tea enjoyed for its taste and aroma. Phlomis species are used to treat various conditions such as diabetes, gastric ulcer, hemorrhoids, inflammation, and wounds. This review aims to summarize recent research on the phytochemistry and pharmacological properties of the genus Phlomis, with particular emphasis on its ethnobotanical uses. The essential oil of Phomis is composed of four chemotypes dominated by monoterpenes (alpha-pinene, limonene and linalool), sesquiterpenes (germacrene D and beta-caryophyllene), aliphalic compounds (9,12,15-octadecatrienoic acid methyl ester), fatty acids (hexadecanoic acid) and other components (trans-phytol, 9,12,15-octadecatrien-1-ol). Flavonoids, iridoids and phenylethyl alcohol constitute the main compounds isolated from Phlomis extracts. The pharmacological activities of some Phlomis species have been investigated. They are described according to antidiabetic, antinociceptive, antiulcerogenic, protection of the vascular system, anti-inflammatory, antiallergic, anticancer, antimicrobial and antioxidant properties. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：183 / 202

页数：20

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