Group B Streptococcus:: global incidence and vaccine development

被引：253

作者：

Johri, Atul Kumar ^{[1
]}

Paoletti, Lawrence C.

Glaser, Philippe

Dua, Meenakshi

Sharma, Puja Kumari

Grandi, Guido

Rappuoli, Rino

机构：

[1] Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India

[2] Jawaharlal Nehru Univ, Sch Environm Sci, New Delhi 110067, India

[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Channing Lab,Dept Med, Boston, MA 02115 USA

[4] Inst Pasteur, URA CNRS 2171, Unite Genom Microorganismes Pathogenes, F-75724 Paris, France

[5] Novartis Vaccines, I-53100 Siena, Italy

来源：

NATURE REVIEWS MICROBIOLOGY | 2006年 / 4卷 / 12期

关键词：

D O I：

10.1038/nrmicro1552

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An ongoing public health challenge is to develop vaccines that are effective against infectious diseases that have global relevance. Vaccines against serotypes of group B Streptococcus ( GBS) that are prevalent in the United States and Europe are not optimally efficacious against serotypes common to other parts of the world. New technologies and innovative approaches are being used to identify GBS antigens that overcome serotypespecificity and that could form the basis of a globally effective vaccine against this opportunistic pathogen. This Review highlights efforts towards this goal and describes a template that can be followed to develop vaccines against other bacterial pathogens.

引用

页码：932 / 942

页数：11

共 110 条

[1] A comparison of selected mRNA and protein abundances in human liver [J].

Anderson, L ;

Seilhamer, J .

ELECTROPHORESIS, 1997, 18 (3-4) :533-537

[2]

[Anonymous], STAT ART VACC RES DE

[3]

Baker C J, 1985, Antibiot Chemother (1971), V35, P281

[4] IMMUNIZATION OF PREGNANT-WOMEN WITH A POLYSACCHARIDE VACCINE OF GROUP-B STREPTOCOCCUS [J].

BAKER, CJ ;

RENCH, MA ;

EDWARDS, MS ;

CARPENTER, RJ ;

HAYS, BM ;

KASPER, DL .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (18) :1180-1185

[5] Group B streptococcal conjugate vaccines [J].

Baker, CJ ;

Edwards, MS .

ARCHIVES OF DISEASE IN CHILDHOOD, 2003, 88 (05) :375-378

[6] CORRELATION OF MATERNAL ANTIBODY DEFICIENCY WITH SUSCEPTIBILITY TO NEONATAL GROUP-B STREPTOCOCCAL INFECTION [J].

BAKER, CJ ;

KASPER, DL .

NEW ENGLAND JOURNAL OF MEDICINE, 1976, 294 (14) :753-756

[7] Identification of novel adhesins from group B streptococci by use of phage display reveals that C5a peptidase mediates fibronectin binding [J].

Beckmann, C ;

Waggoner, JD ;

Harris, TO ;

Tamura, GS ;

Rubens, CE .

INFECTION AND IMMUNITY, 2002, 70 (06) :2869-2876

[8]

BEVANGER L, 1985, ACTA PATH MICRO IM B, V93, P113

[9] The alpha C protein mediates internalization of group B Streptococcus within human cervical epithelial cells [J].

Bolduc, GR ;

Baron, MJ ;

Gravekamp, C ;

Lachenauer, CS ;

Madoff, LC .

CELLULAR MICROBIOLOGY, 2002, 4 (11) :751-758

[10] Induction of cross-reactive antibodies by immunization of healthy adults with types Ia and Ib group B streptococcal polysaccharide-tetanus toxoid conjugate vaccines [J].

Brigtsen, AK ;

Kasper, DL ;

Baker, CJ ;

Jennings, HJ ;

Guttormsen, HK .

JOURNAL OF INFECTIOUS DISEASES, 2002, 185 (09) :1277-1284

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