Routes to fluorinated organic derivatives by nickel mediated C-F activation of heteroaromatics

被引：205

作者：

Braun, T

Perutz, RN

机构：

[1] Univ Bielefeld, Fak Chem, D-33501 Bielefeld, Germany

[2] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 23期

关键词：

D O I：

10.1039/b206154f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New fluorinated azaheterocycles can be synthesised regio- and chemo-selectively via C-F activation of fluorinated precursors at nickel, with subsequent functionalisation and release from the coordination sphere of the metal; the requirements for productive C- F activation are significantly different from those for C-H bond activation.

引用

页码：2749 / 2757

页数：9