A new epimeric pair of mono-THF Annonaceous acetogenins from Goniothalamus gardneri

被引：12

作者：

Chen, Y

Chen, RR

Jiang, Z

Yu, DQ ^{[1
]}

机构：

[1] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

PLANTA MEDICA | 1998年 / 64卷 / 03期

关键词：

Goniothalamus gardneri; Annonaceae; acetogenin; gardnerinin and 34-epi-gardnerinin;

D O I：

10.1055/s-2006-957418

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

From the roots of Goniothalamus gardneri Hook f. et. Thoms (Annonaceae), we have isolated a novel epimeric pair, gardnerinin (1) and 34-epi-gardnerinin (1'), characterized by the presence of a gamma-hydroxymethyl-gamma-lactone moiety. These compounds represent an unusual type of mono-THF Annonaceous acetogenins, bearing one flanking hydroxy group on the hydrocarbon side, and another hydroxy group on the lactone side, that is only one carbon away from the THF ring.

引用

页码：242 / 245

页数：4