The application of cholinesterase potentiometric biosensor for preliminary screening of the toxicity of waste waters

被引：22

作者：

Evtugyn, GA ^{[1
]}

Rizaeva, EP ^{[1
]}

Stoikova, EE ^{[1
]}

Latipova, VZ ^{[1
]}

Budnikov, HC ^{[1
]}

机构：

[1] Kazan State Univ, Ecol Fac, RUS-420008 Kazan, Russia

来源：

ELECTROANALYSIS | 1997年 / 9卷 / 14期

关键词：

toxicity; cholinesterase; biosensor; inhibition; enzyme electrode;

D O I：

10.1002/elan.1140091417

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The application of cholinesterase biosensor for preliminary testing of total pollution of domestic and industrial discharges has been investigated. The results indicate that biosensor-based testing is more sensitive than paramecia bioassay. For numerous samples tested, the inhibition degree of biosensor response exceeds the appropriate value of acute toxicity on Paramecium caudatum. Electrochemical oxidation of the samples, before the biosensor testing readily removes oxidizable compounds which do not effect a real risk of environmental pollution. Simultaneous determination of inhibitory effect, acute toxicity and biochemical (chemical) oxygen demand makes it possible to infer a possible source of contamination of waters.

引用

页码：1124 / 1128

页数：5

共 31 条

[1] ALBERY WJ, 1990, BIOSENS BIOELECTRON, V5, P397
[2] CYANIDE DETERMINATION USING AN AMPEROMETRIC BIOSENSOR BASED ON CYTOCHROME-OXIDASE INHIBITION
AMINE, A
ALAFANDY, M
KAUFFMANN, JM
PEKLI, MN
[J]. ANALYTICAL CHEMISTRY, 1995, 67 (17) : 2822 - 2827
[3] AN ENZYME AMPEROMETRIC SENSOR FOR TOXICANT DETERMINATION
BUDNIKOV, HC
MEDYANTSEVA, EP
BABKINA, SS
[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1991, 310 (1-2): : 49 - 55
[4] Electrochemical biosensors for inhibitor determination: Selectivity and sensitivity control
Budnikov, HC
Evtugyn, GA
[J]. ELECTROANALYSIS, 1996, 8 (8-9) : 817 - 820
[5] DISPOSABLE RUTHENIZED SCREEN-PRINTED BIOSENSORS FOR PESTICIDES MONITORING
CAGNINI, A
PALCHETTI, I
LIONTI, I
MASCINI, M
TURNER, APF
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 1995, 24 (1-3) : 85 - 89
[6] AN ENZYME-IMMOBILIZATION PROCEDURE FOR THE ANALYSIS OF ENZYME-INHIBITING CHEMICALS IN WATER
CHRISTENSEN, GM
RIEDEL, BL
[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1980, 8 (04) : 277 - 282
[7] CHOLINE DERIVATIVES AND SODIUM-FLUORIDE PROTECT ACETYLCHOLINESTERASE AGAINST IRREVERSIBLE INHIBITION AND AGING BY DFP AND PARAOXON
DEHLAWI, MS
ELDEFRAWI, AT
ELDEFRAWI, ME
ANIS, NA
VALDES, JJ
[J]. JOURNAL OF BIOCHEMICAL TOXICOLOGY, 1994, 9 (05): : 261 - 268
[8] A NEW MICRO-DETECTION TUBE FOR CHOLINESTERASE-INHIBITORS IN WATER
DU, TF
ZHOU, SG
TANG, MS
[J]. ENVIRONMENTAL POLLUTION, 1989, 57 (03) : 217 - 222
[9] ELYAMANI H, 1988, TECHNOL CHIM, V8, P112
[10] Influence of surface-active compounds on the response and sensitivity of cholinesterase biosensors for inhibitor determination
Evtugyn, GA
Budnikov, HC
Nikolskaya, EB
[J]. ANALYST, 1996, 121 (12) : 1911 - 1915

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