Highly diastereoselective synthesis of two analogues of dihydrosphingosine

被引：33

作者：

Villard, R ^{[1
]}

Fotiadu, F ^{[1
]}

Buono, G ^{[1
]}

机构：

[1] Ecole Natl Super Synth Proc & Ingn Chim Aix Marse, UMR 6516, F-13397 Marseille 20, France

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(98)00030-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Diastereomeric analogues 8 and 9 of dihydrosphingosine 2 with a shortened alkyl chain were obtained with high diastereoselectivity via addition of n-hexyl magnesium bromide or dihexylzinc to a chiral aldehyde 3, respectively. These compounds are precursors of new potentially hydrosoluble analogues of glycosphingolipides. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：607 / 611

页数：5