Conserved noncoding sequences are reliable guides to regulatory elements

被引：336

作者：

Hardison, RC ^{[1
]}

机构：

[1] Penn State Univ, Dept Biochem & Mol Biol, University Pk, PA 16802 USA

来源：

TRENDS IN GENETICS | 2000年 / 16卷 / 09期

关键词：

D O I：

10.1016/S0168-9525(00)02081-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.

引用

页码：369 / 372

页数：4