Facile, Template-Free Synthesis of Stimuli-Responsive Polymer Nanocapsules for Targeted Drug Delivery

被引：180

作者：

Kim, Eunju ^{[1
,2
]}

Kim, Dongwoo ^{[1
,2
]}

Jung, Hyuntae ^{[1
,2
]}

Lee, Jiyeong ^{[1
,2
]}

Paul, Somak ^{[1
,2
]}

Selvapalam, Narayanan ^{[1
,2
]}

Yang, Yosep ^{[3
]}

Lim, Namseok ^{[3
]}

Park, Chan Gyung ^{[3
]}

Kim, Kimoon ^{[1
,2
]}

机构：

[1] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, Dept Chem, Pohang 790784, South Korea

[2] Pohang Univ Sci & Technol, Div Adv Mat Sci, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol, Dept Mat Sci & Engn, Pohang 790784, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 26期

关键词：

cucurbituril; host-guest systems; nanostructures; polymerization; supramolecular chemistry; ENE CLICK CHEMISTRY; CUCURBITURIL; COMPLEXATION; DERIVATIVES; DENDRIMERS; CAPSULES; SURFACE; PHOTOPOLYMERIZATIONS; PHOTOINITIATORS; NANOPARTICLES;

D O I：

10.1002/anie.201000818

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4405 / 4408

页数：4

共 50 条

[1]

[Anonymous], 2005, ANGEW CHEM INT EDIT

[2]

[Anonymous], 2005, ANGEW CHEM, DOI DOI 10.1002/ANIE.201210267

[3] Novel polymer capsules from amphiphilic graft copolymers and cross-metathesis [J].

Breitenkamp, K ;

Emrick, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (40) :12070-12071

[4] A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity [J].

Choi, Jinny ;

Kim, Jeeyeon ;

Kim, Kimoon ;

Yang, Sung-Tae ;

Kim, Jae-Il ;

Jon, Sangyong .

CHEMICAL COMMUNICATIONS, 2007, (11) :1151-1153

[5] Initiation and kinetics of thiol-ene photopolymerizations without photoinitiators [J].

Cramer, NB ;

Reddy, SK ;

Cole, M ;

Hoyle, C ;

Bowman, CN .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (22) :5817-5826

[6] Photopolymerizations of thiol-ene polymers without photoinitiators [J].

Cramer, NB ;

Scott, JP ;

Bowman, CN .

MACROMOLECULES, 2002, 35 (14) :5361-5365

[7]

De Geest BG, 2007, CHEM SOC REV, V36, P636, DOI 10.1039/b600460c

[8]

Donath E., 1998, ANGEW CHEM, V110, P2323

[9]

Dondoni A., 2008, Angew. Chem, V120, P9133, DOI DOI 10.1002/ANGE.200802516

[10] The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry [J].

Dondoni, Alessandro .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (47) :8995-8997

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