Facile, Template-Free Synthesis of Stimuli-Responsive Polymer Nanocapsules for Targeted Drug Delivery

被引：180

作者：

Kim, Eunju ^{[1
,2
]}

Kim, Dongwoo ^{[1
,2
]}

Jung, Hyuntae ^{[1
,2
]}

Lee, Jiyeong ^{[1
,2
]}

Paul, Somak ^{[1
,2
]}

Selvapalam, Narayanan ^{[1
,2
]}

Yang, Yosep ^{[3
]}

Lim, Namseok ^{[3
]}

Park, Chan Gyung ^{[3
]}

Kim, Kimoon ^{[1
,2
]}

机构：

[1] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, Dept Chem, Pohang 790784, South Korea

[2] Pohang Univ Sci & Technol, Div Adv Mat Sci, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol, Dept Mat Sci & Engn, Pohang 790784, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 26期

关键词：

cucurbituril; host-guest systems; nanostructures; polymerization; supramolecular chemistry; ENE CLICK CHEMISTRY; CUCURBITURIL; COMPLEXATION; DERIVATIVES; DENDRIMERS; CAPSULES; SURFACE; PHOTOPOLYMERIZATIONS; PHOTOINITIATORS; NANOPARTICLES;

D O I：

10.1002/anie.201000818

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4405 / 4408

页数：4

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