The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations

被引：1137

作者：

Christ, Andreas ^{[1
]}

Kainz, Wolfgang ^{[2
]}

Hahn, Eckhart G. ^{[3
]}

Honegger, Katharina ^{[1
]}

Zefferer, Marcel ^{[1
]}

Neufeld, Esra ^{[1
,4
]}

Rascher, Wolfgang ^{[3
]}

Janka, Rolf ^{[3
]}

Bautz, Werner ^{[3
]}

Chen, Ji ^{[5
]}

Kiefer, Berthold ^{[6
]}

Schmitt, Peter ^{[6
]}

Hollenbach, Hans-Peter ^{[6
]}

Shen, Jianxiang ^{[5
]}

Oberle, Michael ^{[1
]}

Szczerba, Dominik ^{[1
]}

Kam, Anthony ^{[7
]}

Guag, Joshua W. ^{[2
]}

Kuster, Niels ^{[1
,4
]}

机构：

[1] Fdn Res Informat Technol Soc ITIS, CH-8004 Zurich, Switzerland

[2] US FDA, CDRH, Silver Spring, MD 20993 USA

[3] Univ Erlangen Nurnberg, Univ Klinikum Erlangen, D-91054 Erlangen, Germany

[4] Swiss Fed Inst Technol ETHZ, CH-8092 Zurich, Switzerland

[5] Univ Houston, Dept Elect & Comp Engn, Houston, TX 77204 USA

[6] Siemens Healthcare, MR Applicat Dev, D-91052 Erlangen, Germany

[7] Johns Hopkins Bayview Med Ctr, Dept Imaging, Baltimore, MD 21224 USA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2010年 / 55卷 / 02期

关键词：

BODY-MASS INDEX; ELECTROMAGNETIC-FIELDS; FREQUENCY-RANGE; HUMAN HEAD; ABSORPTION; TISSUES; SAR; SEGMENTATION; PHANTOMS; EXPOSURE;

D O I：

10.1088/0031-9155/55/2/N01

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.

引用

页码：N23 / N38

页数：16

共 62 条

[21]

Hamerly G., 2002, Proceedings of the Eleventh International Conference on Information and Knowledge Management. CIKM 2002, P600, DOI 10.1145/584792.584890

[22] Modelling the interaction of electromagnetic fields (10 MHz-10 GHz) with the human body: methods and applications [J].

Hand, J. W. .

PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (16) :R243-R286

[23]

*IEEE, 2003, 1528 IEEE

[24] Dosimetric comparison of the specific anthropomorphic mannequin (SAM) to 14 anatomical head models using a novel definition for the mobile phone positioning [J].

Kainz, W ;

Christ, A ;

Kellom, T ;

Seidman, S ;

Nikoloski, N ;

Beard, B ;

Kuster, N .

PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (14) :3423-3445

[25] HDRK-Man: a whole-body voxel model based on high-resolution color slice images of a Korean adult male cadaver [J].

Kim, Chan Hyeong ;

Choi, Sang Hyoun ;

Jeong, Jong Hwi ;

Lee, Choonsik ;

Chung, Min Suk .

PHYSICS IN MEDICINE AND BIOLOGY, 2008, 53 (15) :4093-4106

[26] EM energy absorption in the human body tissues due to UWB antennas [J].

Klemm, M. ;

Troester, G. .

PROGRESS IN ELECTROMAGNETICS RESEARCH-PIER, 2006, 62 :261-280

[27] FORMATION OF HOT SPOTS IN MULTILAYER SPHERES [J].

KRITIKOS, HN ;

SCHWAN, HP .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1976, 23 (02) :168-172

[28]

Kromeyer-Hauschild K, 2001, MONATSSCHR KINDERH, V149, P807, DOI 10.1007/s001120170107

[29] Assessment of induced radio-frequency electromagnetic fields in various anatomical human body models [J].

Kuehn, Sven ;

Jennings, Wayne ;

Christ, Andreas ;

Kuster, Niels .

PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (04) :875-890

[30] Hybrid computational phantoms of the male and female newborn patient: NURBS-based whole-body models [J].

Lee, Choonsik ;

Lodwick, Daniel ;

Hasenauer, Deanna ;

Williams, Jonathan L. ;

Lee, Choonik ;

Bolch, Wesley E. .

PHYSICS IN MEDICINE AND BIOLOGY, 2007, 52 (12) :3309-3333

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