Solution-phase synthesis of 2,6,9-trisubstituted purines

被引:60
作者
Fiorini, MT [1 ]
Abell, C [1 ]
机构
[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England
关键词
D O I
10.1016/S0040-4039(98)00098-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple three-step method for the solution-phase combinatorial synthesis of 2,6,9-trisubstituted purines from 2,6-dichloropurine is described. The synthesis exploits the use of resin capture to remove excess reagent used in the final step. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1827 / 1830
页数:4
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