Gold Nanorods in Photodynamic Therapy, as Hyperthermia Agents, and in Near-Infrared Optical Imaging

被引：335

作者：

Kuo, Wen-Shuo ^{[1
,2
]}

Chang, Chich-Neng ^{[1
]}

Chang, Yi-Ting ^{[1
]}

Yang, Meng-Heng ^{[3
]}

Chien, Yi-Hsin ^{[1
]}

Chen, Shean-Jen ^{[2
]}

Yeh, Chen-Sheng ^{[1
]}

机构：

[1] Natl Cheng Kung Univ, Dept Chem, Tainan 701, Taiwan

[2] Natl Cheng Kung Univ, Dept Engn Sci, Tainan 701, Taiwan

[3] Natl Chung Hsing Univ, Dept Life Sci, Taichung 402, Taiwan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 15期

关键词：

gold; hyperthermia; imaging agents; nanostructures; photodynamic therapy; METAL-ENHANCED FLUORESCENCE; SINGLET OXYGEN GENERATION; TOLUIDINE BLUE; LETHAL PHOTOSENSITIZATION; INDOCYANINE GREEN; CONTRAST AGENTS; QUANTUM YIELD; NANOPARTICLES; SCATTERING; SURFACE;

D O I：

10.1002/anie.200906927

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The best of three worlds: Cold nanorods coated with poly(styrene-alt-maleic acid) (see picture; pink), the photosensitizer indocyanine green (black), and antibodies (green "Y") serve not only as photodynamic therapy and hyperthermia agents to destroy malignant cells, but they also act as optical contrast agents to simultaneously to monitor cells by imaging in the near-IR region. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2711 / 2715

页数：5

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