Conformational diffusion and helix formation kinetics

被引：86

作者：

Hummer, G

García, AE

Garde, S

机构：

[1] NIDDKD, Phys Chem Lab, NIH, Bethesda, MD 20892 USA

[2] Univ Calif Los Alamos Natl Lab, Theoret Biol & Biophys Grp T10, Los Alamos, NM 87545 USA

[3] Rensselaer Polytech Inst, Dept Chem Engn, Troy, NY 12180 USA

来源：

PHYSICAL REVIEW LETTERS | 2000年 / 85卷 / 12期

关键词：

D O I：

10.1103/PhysRevLett.85.2637

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The lime, temperature, and sequence dependences of helix formation kinetics of fully atomistic peptide models in explicit solvent are described quantitatively by a diffusive search within the coil state with barrierless transitions into the helical state. Conformational diffusion leads to nonexponential kinetics and jump-width dependences in temperature jump experiments.

引用

页码：2637 / 2640

页数：4

共 38 条

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