Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions

被引:105
作者
Williams, Berea A. R.
Lund, Kyle
Liu, Yan
Yan, Hao
Chaput, John C. [1 ]
机构
[1] Arizona State Univ, Dept Chem & Biochem, Biodesign Inst, Ctr BioOpt Nanotechnol, Tempe, AZ 85287 USA
[2] Arizona State Univ, Dept Chem & Biochem, Ctr Single Mol Biophys, Biodesign Inst, Tempe, AZ 85287 USA
关键词
DNA; nanostructures; peptide nanoarrays; self-assembly;
D O I
10.1002/anie.200603919
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:3051 / 3054
页数:4
相关论文
共 20 条
[1]   SYNTHESIS FROM DNA OF A MOLECULE WITH THE CONNECTIVITY OF A CUBE [J].
CHEN, JH ;
SEEMAN, NC .
NATURE, 1991, 350 (6319) :631-633
[2]   Synthesis and hybridization analysis of a small library of peptide-oligonucleotide conjugates [J].
Harrison, JG ;
Balasubramanian, S .
NUCLEIC ACIDS RESEARCH, 1998, 26 (13) :3136-3145
[3]   DNA-templated self-assembly of metallic nanocomponent arrays on a surface [J].
Le, JD ;
Pinto, Y ;
Seeman, NC ;
Musier-Forsyth, K ;
Taton, TA ;
Kiehl, RA .
NANO LETTERS, 2004, 4 (12) :2343-2347
[4]   DNA-templated self-assembly of protein and nanoparticle linear arrays [J].
Li, HY ;
Park, SH ;
Reif, JH ;
LaBean, TH ;
Yan, H .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (02) :418-419
[5]   Protein nanoarrays - Aptamer-directed self-assembly of protein arrays on a DNA nanostructure [J].
Liu, Y ;
Lin, CX ;
Li, HY ;
Yan, H .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (28) :4333-4338
[6]  
Liu Y., 2005, ANGEW CHEM, V117, P4407
[7]   Self-assembling a molecular pegboard [J].
Lund, K ;
Liu, Y ;
Lindsay, S ;
Yan, H .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (50) :17606-17607
[8]   Assembly of Borromean rings from DNA [J].
Mao, CD ;
Sun, WQ ;
Seeman, NC .
NATURE, 1997, 386 (6621) :137-138
[9]   DESIGN AND SYNTHESIS OF A KNOT FROM SINGLE-STRANDED-DNA [J].
MUELLER, JE ;
DU, SM ;
SEEMAN, NC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (16) :6306-6308
[10]   Sequence-encoded self-assembly of multiple-nanocomponent arrays by 2D DNA scaffolding [J].
Pinto, YY ;
Le, JD ;
Seeman, NC ;
Musier-Forsyth, K ;
Taton, TA ;
Kiehl, RA .
NANO LETTERS, 2005, 5 (12) :2399-2402