The European Bioinformatics Institute in 2016: Data growth and integration

被引：169

作者：

Cook, Charles E. ^{[1
]}

Bergman, Mary Todd ^{[1
]}

Finn, Robert D. ^{[1
]}

Cochrane, Guy ^{[1
]}

Birney, Ewan ^{[1
]}

Apweiler, Rolf ^{[1
]}

机构：

[1] European Bioinformat Inst EMBL EBI, European Mol Biol Lab, Wellcome Genome Campus, Cambridge CB10 1SD, England

来源：

NUCLEIC ACIDS RESEARCH | 2016年 / 44卷 / D1期

关键词：

GENOME; ANNOTATION; RESOURCE; SERVICES; SEARCH; DRUG;

D O I：

10.1093/nar/gkv1352

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New technologies are revolutionising biological research and its applications by making it easier and cheaper to generate ever-greater volumes and types of data. In response, the services and infrastructure of the European Bioinformatics Institute (EMBLEBI, www.ebi.ac.uk) are continually expanding: total disk capacity increases significantly every year to keep pace with demand (75 petabytes as of December 2015), and interoperability between resources remains a strategic priority. Since 2014 we have launched two new resources: the European Variation Archive for genetic variation data and EMPIAR for two-dimensional electron microscopy data, as well as a Resource Description Framework platform. We also launched the Embassy Cloud service, which allows users to run large analyses in a virtual environment next to EMBL-EBI's vast public data resources.

引用

页码：D20 / D26

页数：7

共 45 条

[1]

[Anonymous], 2012, Nature

[2]

[Anonymous], NUCL ACIDS RES

[3] UniProt: a hub for protein information [J].

Bateman, Alex ;

Martin, Maria Jesus ;

O'Donovan, Claire ;

Magrane, Michele ;

Apweiler, Rolf ;

Alpi, Emanuele ;

Antunes, Ricardo ;

Arganiska, Joanna ;

Bely, Benoit ;

Bingley, Mark ;

Bonilla, Carlos ;

Britto, Ramona ;

Bursteinas, Borisas ;

Chavali, Gayatri ;

Cibrian-Uhalte, Elena ;

Da Silva, Alan ;

De Giorgi, Maurizio ;

Dogan, Tunca ;

Fazzini, Francesco ;

Gane, Paul ;

Cas-tro, Leyla Garcia ;

Garmiri, Penelope ;

Hatton-Ellis, Emma ;

Hieta, Reija ;

Huntley, Rachael ;

Legge, Duncan ;

Liu, Wudong ;

Luo, Jie ;

MacDougall, Alistair ;

Mutowo, Prudence ;

Nightin-gale, Andrew ;

Orchard, Sandra ;

Pichler, Klemens ;

Poggioli, Diego ;

Pundir, Sangya ;

Pureza, Luis ;

Qi, Guoying ;

Rosanoff, Steven ;

Saidi, Rabie ;

Sawford, Tony ;

Shypitsyna, Aleksandra ;

Turner, Edward ;

Volynkin, Vladimir ;

Wardell, Tony ;

Watkins, Xavier ;

Zellner, Hermann ;

Cowley, Andrew ;

Figueira, Luis ;

Li, Weizhong ;

McWilliam, Hamish .

NUCLEIC ACIDS RESEARCH, 2015, 43 (D1) :D204-D212

[4] Lifelong learning for all in biomedicine [J].

Brooksbank, Cath ;

Johnson, Claire .

NATURE, 2015, 524 (7566) :415-415

[5] The European Bioinformatics Institute's data resources 2014 [J].

Brooksbank, Catherine ;

Bergman, Mary Todd ;

Apweiler, Rolf ;

Birney, Ewan ;

Thornton, Janet .

NUCLEIC ACIDS RESEARCH, 2014, 42 (D1) :D18-D25

[6] Saccharomyces Genome Database: the genomics resource of budding yeast [J].

Cherry, J. Michael ;

Hong, Eurie L. ;

Amundsen, Craig ;

Balakrishnan, Rama ;

Binkley, Gail ;

Chan, Esther T. ;

Christie, Karen R. ;

Costanzo, Maria C. ;

Dwight, Selina S. ;

Engel, Stacia R. ;

Fisk, Dianna G. ;

Hirschman, Jodi E. ;

Hitz, Benjamin C. ;

Karra, Kalpana ;

Krieger, Cynthia J. ;

Miyasato, Stuart R. ;

Nash, Rob S. ;

Park, Julie ;

Skrzypek, Marek S. ;

Simison, Matt ;

Weng, Shuai ;

Wong, Edith D. .

NUCLEIC ACIDS RESEARCH, 2012, 40 (D1) :D700-D705

[7] Pfam: the protein families database [J].

Finn, Robert D. ;

Bateman, Alex ;

Clements, Jody ;

Coggill, Penelope ;

Eberhardt, Ruth Y. ;

Eddy, Sean R. ;

Heger, Andreas ;

Hetherington, Kirstie ;

Holm, Liisa ;

Mistry, Jaina ;

Sonnhammer, Erik L. L. ;

Tate, John ;

Punta, Marco .

NUCLEIC ACIDS RESEARCH, 2014, 42 (D1) :D222-D230

[8] LOVD v.2.0: The Next Generation in Gene Variant Databases [J].

Fokkema, Ivo F. A. C. ;

Taschner, Peter E. M. ;

Schaafsma, Gerard C. P. ;

Celli, J. ;

Laros, Jeroen F. J. ;

den Dunnen, Johan T. .

HUMAN MUTATION, 2011, 32 (05) :557-563

[9] Efficient storage of high throughput DNA sequencing data using reference-based compression [J].

Fritz, Markus Hsi-Yang ;

Leinonen, Rasko ;

Cochrane, Guy ;

Birney, Ewan .

GENOME RESEARCH, 2011, 21 (05) :734-740

[10] Biocuration of functional annotation at the European nucleotide archive [J].

Gibson, Richard ;

Alako, Blaise ;

Amid, Clara ;

Cerdeno-Tarraga, Ana ;

Cleland, Iain ;

Goodgame, Neil ;

ten Hoopen, Petra ;

Jayathilaka, Suran ;

Kay, Simon ;

Leinonen, Rasko ;

Liu, Xin ;

Pallreddy, Swapna ;

Pakseresht, Nima ;

Rajan, Jeena ;

Rossello, Marc ;

Silvester, Nicole ;

Smirnov, Dmitriy ;

Toribio, Ana Luisa ;

Vaughan, Daniel ;

Zalunin, Vadim ;

Cochrane, Guy .

NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) :D58-D66

← 1 2 3 4 5 →