Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats

被引：113

作者：

Huang, Ling ^{[2
]}

Wen, Kewei ^{[1
]}

Gao, Xuan ^{[1
]}

Liu, Yonghong ^{[1
]}

机构：

[1] Chinese Acad Sci, S China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China

[2] Guangdong Prov Peoples Hosp, Dept Oncol, Guangzhou, Guangdong, Peoples R China

来源：

PHARMACEUTICAL BIOLOGY | 2010年 / 48卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Fucoidan; hyperlipidemic rats; hypolipidemic effect; Laminaria japonica Aresch; SULFATED POLYSACCHARIDE FRACTIONS; CHOLESTEROL-FED RATS; BROWN SEAWEED; ANTIOXIDANT ACTIVITY; MARINE-ALGAE; ANTICOAGULANT; CONSTITUENTS; EXTRACTS; MICE;

D O I：

10.3109/13880200903150435

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In this study, we investigated the effect of fucoidan polysaccharide sulfuric acid ester (FPS) from Laminaria japonica Aresch (Laminariaceae) on hyperlipidemic rats. FPS notably reduced the concentration of serum total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) of hyperlipidemic rats and increased the concentration of high-density lipoprotein cholesterol (HDL-C) and the activities of lipoprotein lipase (LPL), hepatic lipoprotein (HL), and lecithin cholesterol acyltransferase (LCAT).</.

引用

页码：422 / 426

页数：5

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