Multispectral photoacoustic coded excitation imaging using unipolar orthogonal Golay codes

被引：51

作者：

Mienkina, Martin P. ^{[1
]}

Friedrich, Claus-Stefan ^{[1
]}

Gerhardt, Nils C. ^{[1
]}

Beckmann, Martin F. ^{[1
]}

Schiffner, Martin F. ^{[1
]}

Hofmann, Martin R. ^{[1
]}

Schmitz, Georg ^{[1
]}

机构：

[1] Ruhr Univ Bochum, D-44780 Bochum, Germany

来源：

OPTICS EXPRESS | 2010年 / 18卷 / 09期

关键词：

IN-VIVO; LASER-DIODE; TOMOGRAPHY; SYSTEM; BRAIN;

D O I：

10.1364/OE.18.009076

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present a method to speed up the acquisition of multispectral photoacoustic data sets by using unipolar orthogonal Golay codes as excitation sequences for the irradiation system. Multispectral photoacoustic coded excitation (MS-PACE) allows acquiring photoacoustic data sets for two irradiation wavelengths simultaneously and separating them afterwards, thus improving the SNR or speeding up the measurement. We derive an analytical estimation of the SNR improvement using MS-PACE compared to time equivalent averaging. We demonstrate the feasibility of the method by successfully imaging a phantom composed of two dyes using unipolar orthogonal Golay codes as excitation sequence for two high power laser diodes operating at two different wavelengths. The experimental results show very good agreement with the theoretical predictions. (C) 2010 Optical Society of America

引用

页码：9076 / 9087

页数：12

共 16 条

[1] Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging [J].