The modulation of host cell apoptosis by intracellular bacterial pathogens

被引：202

作者：

Gao, LY

Kwaik, YA

机构：

[1] Univ Calif San Francisco, Program Microbial Pathogenesis & Host Def, San Francisco, CA 94143 USA

[2] Univ Kentucky, Dept Microbiol & Immunol, Chandler Med Ctr, Lexington, KY 40536 USA

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 07期

关键词：

D O I：

10.1016/S0966-842X(00)01784-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent years have witnessed significant advances in unraveling the elegant mechanisms by which intracellular bacterial pathogens induce and/or block apoptosis, which can influence disease progression. This intriguing aspect of the host-pathogen interaction adds another fascinating dimension to our understanding of the exploitation of host cell biology by intracellular bacterial pathogens.

引用

页码：306 / 313

页数：8

共 74 条

[71] Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked [J].