Determination of Nicotinamide in Food and Human Fluid Samples by Capillary Electrophoresis Chemiluminescence

被引：2

作者：

Han, Suqin ^{[1
]}

Wu, Kegang ^{[1
]}

机构：

[1] Shanxi Normal Univ, Sch Chem & Mat Sci, Linfen 041004, Peoples R China

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2015年 / 62卷 / 01期

关键词：

Capillary electrophoresis; Chemiluminescence; Nicotinamide; Human urine and plasma; Yogurt; ACID; CHROMATOGRAPHY; LUMINESCENCE;

D O I：

10.1002/jccs.201400207

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A rapid and simple capillary electrophoresis (CE) coupled with chemiluminescence (CL) detection was proposed for analysis of nicotinamide. This method was based on the inhibitory effect of nicotinamide to CL reaction of luminol-K3Fe(CN)(6) in alkaline aqueous solution. Under the optimal conditions, nicotinamide can be assayed in the range of 0.01-10.0 mu M with a limit of detection of 3.0 nM. The whole analysis process can be completed within 11 mm. The relative standard deviations of the signal intensity and the migration time were 3.0% and 1.5% for a standard sample at 0.1 mu M, respectively. The presented CE-CL method was successfully applied to the determination of nicotinamide in yogurt, human urine and plasma samples.

引用

页码：73 / 78

页数：6

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